The short version: Adentris and MDaudit both protect revenue through documentation and billing compliance, but they are built for different settings. MDaudit is a cloud billing-compliance and revenue-integrity platform that automates coding and billing audits, denial-risk monitoring, and audit workflows for large health systems. Adentris is a revenue integrity and documentation compliance layer purpose-built for behavioral health and SUD, with rules like ASAM level of care and 42 CFR Part 2 and an appeals and denials module, running on any EHR. If you are a large health system, MDaudit is built for that. If you run a behavioral health or SUD program, that specialty depth is the deciding factor.
Both protect revenue through compliance, so the comparison comes down to setting and specialty depth. Here is an honest comparison.
What Adentris does
Adentris is an AI platform for revenue integrity and documentation compliance built specifically for behavioral health and SUD programs. It works on top of the EHR you already run, connecting through an API or HL7 where one exists (for example Alleva, Pimsy, Kipu, Epic, or Athenahealth) and through a secure web agent where it does not, so there is no migration. It reviews notes in real time and flags the elements that get behavioral health claims denied before the claim is submitted: medical necessity, ASAM level-of-care justification, treatment plan updates, group therapy attendance, service units, signature timing, and 42 CFR Part 2 consent. When something is missing, it drafts the correction for the clinician to accept, and it pairs documentation review with an appeals and denials module. Adentris is HIPAA compliant and SOC 2 certified, with 42 CFR Part 2 controls and BAAs in place.
What MDaudit does
MDaudit is a cloud-based billing-compliance and revenue-integrity platform used by many of the largest US health systems. It automates coding and billing audits, monitors denial risk, and manages audit workflows across the organization, and it acquired Streamline Health in 2025. For large health systems that want enterprise billing-compliance and audit automation, MDaudit is a strong, established option.
Adentris vs MDaudit at a glance
| Adentris | MDaudit | |
|---|---|---|
| Best for | BH and SUD programs focused on denials and compliance | Large health systems (billing compliance) |
| Primary job | Catch and fix denial-driving gaps before the claim is submitted | Automate coding and billing audits and denial monitoring |
| Review timing | Real time, before the claim is submitted | Pre- and post-bill auditing |
| Is it a scribe? | No, it reviews the note, however it was written | No, it is a billing-compliance and audit platform |
| SUD depth | ASAM level of care and 42 CFR Part 2 built in | General health-system focus |
| EHR fit | Any EHR via API, HL7, or a secure web agent (no migration) | Billing and coding data integrations |
| Compliance focus | Payer claim denials and revenue integrity | Billing compliance and revenue integrity |
| Denials | Paired appeals and denials module | Denial-risk monitoring and audit workflows |
Capabilities change quickly in this market, so confirm current details with each vendor before you decide.
Which should you choose?
Both use compliance to protect revenue, so the real question is setting and specialty depth. MDaudit is built for enterprise billing-compliance and audit across a large health system. Adentris is built specifically for behavioral health and SUD, where denials turn on ASAM level of care, medical necessity, group therapy attendance, service units, and 42 CFR Part 2 consent. Adentris understands those rules, drafts the correction before submission, pairs review with an appeals and denials module, and runs on any EHR through a secure web agent, including systems that do not expose a clean integration. For a behavioral health or SUD program, that depth and reach are the practical differences.
- Choose MDaudit if you are a large health system that wants enterprise billing-compliance, coding and billing audits, and denial-risk monitoring.
- Choose Adentris if you run a behavioral health or SUD program and want documentation reviewed against the specialty rules that drive your denials, ASAM, medical necessity, and 42 CFR Part 2, with drafted fixes and a paired appeals module, on any EHR.
Adentris as an MDaudit alternative for behavioral health and SUD
If you are evaluating MDaudit for a behavioral health or SUD program, the question is specialty fit. Enterprise billing-compliance and audit built for large health systems are valuable at that scale, but behavioral health claims are denied for field-specific reasons: an unjustified ASAM level of care, a missing medical necessity statement, group therapy attendance and service units that do not line up, or a 42 CFR Part 2 consent that was not captured. Adentris is built around those rules, drafts the fix before submission, pairs it with an appeals and denials workflow, and runs on any EHR through an API, HL7, or a secure web agent, which makes it the purpose-built choice for behavioral health and SUD.
How Adentris helps
For behavioral health and SUD organizations, the biggest revenue leak is documentation, and it is specific: medical necessity that was never shown, missing ASAM justification, a Part 2 consent that was not captured. Adentris reviews every chart in real time inside your existing EHR and flags exactly those gaps before the claim is filed, then drafts the fix, and it pairs that with an appeals and denials module so compliance and revenue integrity live in one place. In practice that means fewer denied claims, less audit exposure, and far less time spent reworking documentation after a payer pushes back. Adentris is HIPAA compliant and SOC 2 certified, with 42 CFR Part 2 controls and BAAs in place. To see it on your own charts, book a 30-minute call with our team.
The bottom line
For enterprise billing-compliance and audit, MDaudit is a strong fit. For a behavioral health or SUD program, Adentris brings the specialty depth, ASAM, medical necessity, and 42 CFR Part 2, drafts the fix before submission, and pairs it with appeals, on any EHR.
Related reading
- AI chart review tools for behavioral health
- Best behavioral health documentation compliance software
- Behavioral health payer audit readiness solutions
Frequently asked questions
What is the difference between Adentris and MDaudit?
MDaudit is a cloud billing-compliance and revenue-integrity platform that automates coding and billing audits and denial-risk monitoring for large health systems. Adentris is a revenue integrity and documentation compliance layer purpose-built for behavioral health and SUD, with ASAM and 42 CFR Part 2 rules and an appeals module, running on any EHR. The main difference is setting and specialty depth: enterprise health systems versus behavioral health and SUD.
Can Adentris and MDaudit be used together?
Yes. They solve different halves of the problem, so a program can use MDaudit to run billing-compliance audits and Adentris to verify the documentation supports the claim and to handle appeals. Adentris reviews the note however it was written, so it fits alongside MDaudit.
Is Adentris a good alternative to MDaudit?
For programs whose problem is denials and audit exposure rather than enterprise billing-compliance and audit, yes. Adentris focuses on catching and correcting the behavioral health and SUD gaps that drive denials before submission, with ASAM and 42 CFR Part 2 built in and an appeals and denials module, and it runs on any EHR without a migration.
Which is better for a substance use disorder program?
For SUD, the claims that get denied usually turn on ASAM level of care, medical necessity, and 42 CFR Part 2, which Adentris is built around with real-time, pre-submission review and drafted corrections. MDaudit is strong for enterprise billing-compliance, audit automation, and denial-risk monitoring. Programs that want SUD-specific compliance depth and denials support often lean Adentris.
About the author: Sergey Yudovskiy is the Chief Product Officer of Adentris, which builds AI for revenue integrity and documentation compliance in behavioral health and substance use disorder care.